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Table 2 IFP1 Variation and Association with Type 2 Diabetes

From: Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans

Name Variat dbSNP Posit Popul Frequency, Caucasian Frequency, Af. American
      Cases Controls Cases Controls
SNP1 C/T ------ -3766 AA/Cauc 0.183 (0.143, 0.223) 0.192 (0.152, 0.232) 0.144 (0.118,0.170) 0.2101 (0.167,0.253)
SNP3 T/C rs2293942 -2890 Cauc 0.278 (0.232, 0.324) 0.249 (0.206, 0.292) ------ ------
SNP4 A/T rs2293943 -2877 AA/Cauc 0.339 (0.291, 0.387) 0.369 (0.321,0.417) 0.289 (0.255,0.323) 0.3702 (0.321,0.419)
SNP6 G/T ------ -1263 AA/Cauc 0.196 (0.156, 0.236) 0.189 (0.151, 0.229) 0.119 (0.091,0.147) 0.129 (0.093, 0.165)
SNP5 C/T rs4002827 -992 AA ------ ------ 0.071 (0.048, 0.094) 0.044 (0.021, 0.067)
SNP2 G/A ------ -279 AA/Cauc 0.458 (0.408, 0.508) 0.429 0.379, 0.479) 0.114 (0.086, 0.142) 0.139 (0.101, 0.177)
SNP11 (G)4/(G)3 ------ -108 AA/Cauc 0.182 (0.143, 0.221) 0.177 (0.138, 0.216) 0.134 (0.108, 0.160) 0.2173 (0.175, 0.259)
SNP8 G/T rs4430606 +918 AA/Cauc 0.197 (0.157, 0.237) 0.191 (0.152, 0.232) 0.115 (0.087, 0.143) 0.133 (0.096, 0.170)
InsCCG243 InsCCG ------ +4437 AA ----- ----- 0.091 (0.069, 0.113) 0.0604 (0.035, 0.085)
  1. Name, name from Figure 1 and text; variant, major/minor allele except for InsCCG243, in which the insertion is the minor allele; dbSNP, catalog number in public database if available; position, location relative to ATG start; Populat, population in which variant was detected, AA is African American, Cauc is Caucasian; frequency, minor allele frequency. Frequencies are shown with 95% confidence intervals in parentheses. Significance by Fisher Exact test: 1p = 0.007;2p = 0.008; 3p = 0.0008; 4p = 0.088; simulated p values based on 10,000 replicates were 0.027, 0.029, 0.002, and 0.28, for SNP1, SNP4, SNP11, and InsCCG243, respectively. No other simulated p values approached significance.