Table 2 Allelic frequencies and percentage of transmission of IL-1α, IL-1β, IL-1RN, IL-18, RANTES and MCP-1 genetic variants in CD families.
From: Association study of functional genetic variants of innate immunity related genes in celiac disease
Alelle frequency in parents (%) | T:NT | % T | P | |
|---|---|---|---|---|
IL-1A -551 | ||||
C | 70.4 | 111:125 | 47 | 0.08 |
T | 29.6 | 52:38 | 58 | 0.08 |
IL-1B -889 | ||||
T | 67.6 | 110:111 | 49.7 | NS |
C | 32.4 | 47:46 | 50.5 | NS |
IL-1RN VNTR | ||||
1 | 71.6 | 107:107 | 50 | NS |
2 | 26.8 | 43:42 | 50.6 | NS |
3 | 1.6 | 2:2 | 50 | NS |
IL-18 -607 | ||||
C | 61.7 | 102:103 | 49.7 | NS |
A | 38.3 | 59:58 | 50.4 | NS |
IL-18 -137 | ||||
G | 75.9 | 124:124 | 50 | NS |
C | 24.1 | 47:47 | 50 | NS |
RANTES -28 | ||||
C | 84.1 | 155:148 | 51 | 0.04 |
G | 15.9 | 3:10 | 23 | 0.04 |
RANTES -403 | ||||
G | 85.7 | 141:128 | 52 | 0.06 |
A | 14.3 | 23:36 | 39 | 0.06 |
MCP-1 | ||||
A | 72.8 | 117:129 | 47 | NS |
G | 27.2 | 48:36 | 57 | NS |