Skip to main content
Figure 1 | BMC Medical Genetics

Figure 1

From: Spinocerebellar ataxia type 17: Report of a family with reduced penetrance of an unstable Gln49TBP allele, haplotype analysis supporting a founder effect for unstable alleles and comparative analysis of SCA17 genotypes

Figure 1

Pedigrees and haplotype analysis. Pedigrees of families A and B, including six-locus haplotypes based on five 6q-telomeric microsatellite markers (D6S1719, D6S264, D6S281, D6S446, D6S1590) and closely downstream located polymorphic poly-Gln encoding trinucleotide stretch within TBP. Alleles of the microsatellites are denoted by numbers 1 – 8, TBP alleles are denoted by the number of Gln-encoding trinucleotides. SCA17-linked alleles are boxed as well as the disease haplotype D6S446 and D6S1590.

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us