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Table 6 3'APOB-VNTR absolute (Abs.) and Relative (Rel.) genotypic and allelic frequencies (± Standard Error) in CD-H and CD-L patients and in sex and age matched controls (males; 46–80 year age range). Values expected at Hardy-Weinberg equilibrium (HWE) are in parenthesis. Alleles:S < 35 repeats;M 35–39 repeats;L >39 repeats.

From: A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

  CD-H patients (n = 40) CD-L patients (n = 40) Controls (n = 105)
Genotype Abs. (HWE) Rel. ± S.E. Abs. (HWE) Rel. ± S.E. Abs. (HWE) Rel. ± S.E.
SS 2 (1.4) 0.05 ± 0.03 1 (0.8) 0.02 ± 0.02 4 (5.3) 0.04 ± 0.02
SM 6 (8.6) 0.15 ± 0.06 9 (7.6) 0.23 ± 0.07 35 (31.3) 0.33 ± 0.05
SL 5 (3.6) 0.12 ± 0.05 0 (1.9) 0 4 (5.4) 0.04 ± 0.02
MM 15 (13.2) 0.38 ± 0.08 17 (18.9) 0.43 ± 0.08 43 (46.0) 0.41 ± 0.05
ML 10 (10.9) 0.25 ± 0.07 12 (9.6) 0.30 ± 0.07 18 (15.9) 0.17 ± 0.04
LL 2 (2.2) 0.05 ± 0.03 1 (1.2) 0.02 ± 0.02 1 (1.4) 0.01 ± 0.01
Alleles Abs. Rel. ± S.E. Abs. Rel ± S.E. Abs. Rel. ± S.E.
S 15 0.19 ± 0.04 11 0.14 ± 0.04 47 0.22 ± 0.03
M 46 0.57 ± 0.06 55 0.69 ± 0.05 139 0.66 ± 0.03
L 19 0.24 ± 0.05 14 0.17 ± 0.04 24 0.11 ± 0.02