Table 6 3'APOB-VNTR absolute (Abs.) and Relative (Rel.) genotypic and allelic frequencies (± Standard Error) in CD-H and CD-L patients and in sex and age matched controls (males; 46–80 year age range). Values expected at Hardy-Weinberg equilibrium (HWE) are in parenthesis. Alleles:S < 35 repeats;M 35–39 repeats;L >39 repeats.
CD-H patients (n = 40) | CD-L patients (n = 40) | Controls (n = 105) | ||||
|---|---|---|---|---|---|---|
Genotype | Abs. (HWE) | Rel. ± S.E. | Abs. (HWE) | Rel. ± S.E. | Abs. (HWE) | Rel. ± S.E. |
SS | 2 (1.4) | 0.05 ± 0.03 | 1 (0.8) | 0.02 ± 0.02 | 4 (5.3) | 0.04 ± 0.02 |
SM | 6 (8.6) | 0.15 ± 0.06 | 9 (7.6) | 0.23 ± 0.07 | 35 (31.3) | 0.33 ± 0.05 |
SL | 5 (3.6) | 0.12 ± 0.05 | 0 (1.9) | 0 | 4 (5.4) | 0.04 ± 0.02 |
MM | 15 (13.2) | 0.38 ± 0.08 | 17 (18.9) | 0.43 ± 0.08 | 43 (46.0) | 0.41 ± 0.05 |
ML | 10 (10.9) | 0.25 ± 0.07 | 12 (9.6) | 0.30 ± 0.07 | 18 (15.9) | 0.17 ± 0.04 |
LL | 2 (2.2) | 0.05 ± 0.03 | 1 (1.2) | 0.02 ± 0.02 | 1 (1.4) | 0.01 ± 0.01 |
Alleles | Abs. | Rel. ± S.E. | Abs. | Rel ± S.E. | Abs. | Rel. ± S.E. |
S | 15 | 0.19 ± 0.04 | 11 | 0.14 ± 0.04 | 47 | 0.22 ± 0.03 |
M | 46 | 0.57 ± 0.06 | 55 | 0.69 ± 0.05 | 139 | 0.66 ± 0.03 |
L | 19 | 0.24 ± 0.05 | 14 | 0.17 ± 0.04 | 24 | 0.11 ± 0.02 |