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Table 1 Diagnostic criteria used to identify CD-H and CD-L patients with Cardiovascular Atherosclerotic Disease (CD)

From: A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

Patients with Cardiovascular Atherosclerotic Disease (CD)

Coronary Artery Disease

  

- Myocardial Infarction

assessment of myocardial ischaemia (exercise test and/or myocardial perfusion scintigraphy)

- Angina Pectoris

  

- PTCA (Percutaneous Transfemoral Coronary Angioplasty)

  

- CABG (Coronary Artery By-pass Graft)

  
 

and/or

 

Carotid Atherosclerosis

assessment of stenosis ≤50%, occlusion (echo-color-doppler)

 

and/or

 

Peripheral Arterial Disease

echo-color-doppler; Index's Windsor <0.8

and with dyslipidemia

HDL-Cholesterol

 

≤35 mg/dl (CD-H patients)*

LDL-Cholesterol

 

≥170 mg/dl (CD-L patients)*

With or Without

  

Tryglycerides

 

≥170 mg/dl

  1. *Cutoff values were chosen on the basis of the average serum levels of HDL-C and LDL-C in southern Italian adult males not affected by any clinically manifest disease.