Table 1 Different parametric models utilized for the linkage analysis
Model | Allele Frequency | Penetrance in DD:Dd susceptibility allele carriers | Penetrance in dd normal homozygotes |
|---|---|---|---|
1 | 0.0133 | 0.90 | 0.00 |
2 | 0.0133 | 0.80 | 0.00 |
3 | 0.0133 | 0.80 | 0.05 |
4 | 0.0133 | 0.60 | 0.15 |
5 | 0.05 | 0.90 | 0.00 |
6 | 0.05 | 0.80 | 0.00 |
7 | 0.05 | 0.80 | 0.05 |
8 | 0.05 | 0.60 | 0.15 |
9 | 0.10 | 0.90 | 0.00 |
10 | 0.10 | 0.80 | 0.00 |
11 | 0.10 | 0.80 | 0.05 |
12 | 0.10 | 0.60 | 0.15 |