From: The impact of population heterogeneity on risk estimation in genetic counseling
 |  | AB NE(c) | AB E(d) | BB NE | |||
---|---|---|---|---|---|---|---|
rAB,NE (a) | rAA,E (b) | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | -0.1090 | 0.0203 | -0.1286 | 0.0465 | 0.0177 | 0.0177 |
 | 0.4 | -0.0663 | 0.0175 | -0.2135 | 0.0574 | 0.0550 | 0.0171 |
 | 0.6 | -0.0312 | 0.0176 | -0.3090 | 0.0718 | 0.1079 | 0.0186 |
 | 0.8 | 0.0080 | 0.0171 | -0.3856 | 0.0846 | 0.1884 | 0.0217 |
0.6 | 0.2 | -0.4019 | 0.0422 | -0.2663 | 0.0648 | -0.0520 | 0.0172 |
 | 0.4 | -0.3671 | 0.0387 | -0.3400 | 0.0773 | -0.0071 | 0.0163 |
 | 0.6 | -0.3330 | 0.0359 | -0.4214 | 0.0911 | 0.0539 | 0.0175 |
 | 0.8 | -0.2949 | 0.0326 | -0.4846 | 0.1023 | 0.1396 | 0.0202 |
 |  | BB E | AA NE | AA E | |||
rAB,NE | rAA,E | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | -0.0211 | 0.0383 | -0.0432 | 0.0414 | -0.0585 | 0.0729 |
 | 0.4 | -0.1316 | 0.0368 | -0.0894 | 0.0466 | -0.1820 | 0.1120 |
 | 0.6 | -0.2365 | 0.0400 | -0.1189 | 0.0541 | -0.2964 | 0.1585 |
 | 0.8 | -0.3079 | 0.0439 | -0.1498 | 0.0605 | -0.3981 | 0.2054 |
0.6 | 0.2 | 0.1094 | 0.0436 | -0.0775 | 0.0460 | 0.0268 | 0.0705 |
 | 0.4 | -0.0138 | 0.0377 | -0.1213 | 0.0529 | -0.1033 | 0.0874 |
 | 0.6 | -0.1335 | 0.0373 | -0.1473 | 0.0602 | -0.2263 | 0.1296 |
 | 0.8 | -0.2158 | 0.0400 | -0.1746 | 0.0663 | -0.3363 | 0.1786 |