Figure 2

Schematic of extent of deletions for 12 patients in the literature with deletions characterized at a molecular level. The black boxes indicate regions where the patients are not deleted. White boxes indicate the minimum extent of the deletion. Grey boxes indicate markers that may or may not be deleted. Genes in this region are listed in bold print. The genetic distance of markers, in Mb (megabases) from the telomere, are also indicated. The source of the information is as follows: Patient A [19], Patient B [28], Patient C is case 2 from [25] and CA from 1, Patients D-G [18], Patient H [10] and SG from [1], Patient I is case 1 from [25] and BD from [1], Patient J is HH from [1], Patient K is JW from [1], Patient L is case 2 from [5].