Table 2 Microsatellite status and immunohistochemical staining of tumor tissue, result of sequencing analysis in all investigated patients.
Patient ID | MS-status | Immunohistochemical staining of tumor tissue | Gene | Exon | Mutation | Length of predicted protein after truncation |
|---|---|---|---|---|---|---|
0546-2 | MSI-H | MLH1 neg, MSH2 pos, MSH6 pos | MLH1 | 19 | c.2198_2199insAACA [p.N733fsX745] | Cd 745 |
0699-3 | MSI-H | MLH1 neg, MSH2 pos, MSH6 pos | MLH1 | 18 | c.2076_2077delTG [p.G693fsX702] | Cd 702 |
0545-0 | MSI-H | MSH2 neg, MSH6 neg, MLH1 pos | MSH2 | 5 | c.810_811delGT [p.C271fsX282] | Cd 281 |
0729-5 | MSI-H | MSH2 red, MSH6 neg, MLH1 pos | MSH2 | 4 | c.763_766delAGTGinsTT [p.F255fsX282] | Cd 282 |
0660-6 | MSI-H | MSH2 neg, MSH6 neg, MLH1 pos | MSH2 | 5 | c.873_876delGACT [p.L292fsX298] | Cd 299 |
0531-X | MSI-H | MSH2 pos, MSH6 neg, MLH1 pos. | MSH6 | 4 | c.1421_1422dupTG [p.C475fsX480] | Cd 480 |