Table 1 Pedigree information and clinical diagnosis of the investigated patients
Patient ID | Clinical diagnosis | Manifestation patient (age of diagnosis) | Manifestation family members (age of diagnosis) |
|---|---|---|---|
0546-2 | AMS II | CRC (32) | Mother: adenocarcinoma in the small pelvis (39) brother of mother: CRC (35) sister of mother: endometrial carcinoma (35) sister of mother. endometrial carcinoma (53), CRC (54) grandfather: CRC (42) sister of grandfather: CRC (66) sister of grandfather: CRC (48) brother of grandfather: gastric cancer (34) |
0699-3 | B2, 3 and 4/Br1, 2, and 4 | CRC (40; 53) | Mother: breast cancer (45) grandmother: CRC (70) cousin of mother: endometrial carcinoma (45) cousin of mother: CRC (40); endometrial carcinoma (48) daughter of cousin: CRC (33) |
0545-0 | B2,3 and 4/Br1, 2 and 4 | CRC (29) | Father: CRC (52; 55; 58) |
0729-5 | AMS I | CRC (44; 46; 54) | Father: CRC (55) Grandfather CRC (unknown age) |
0660-6 | AMS I | CRC (42) | mother: CRC (30 and 57) grandmother: endometrial carcinoma (47), lung cancer (48) sister of grandmother: CRC (51) sister of grandmother: endometrial carcinoma (50) brother of grandmother: CRC (53 and 65) |
0531-X | B7/Br1 | colon adenoma (39; 41) | Sister: colon adenoma (41) Grandmother: CRC (40) |