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Table 3 No significant difference in Leu10Pro polymorphism between patient and control groups could be revealed, although the exchange of leucine by proline at codon 10 was positively correlated with Arg25Pro genotype calculated by Yates corrected Chi-square test (p < 0.025).

From: Analysis of polymorphic TGFB1codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults

Cleft patients

 

Leu10Leu

Leu10Pro

Pro10Pro

Arg25Arg

19

30

9

Arg25Pro

0

2

0

Sum

19

32

9

Controls

 

Leu10Leu

Leu10Pro

Pro10Pro

Arg25Arg

22

24

4

Arg25Pro

0

8

2

Sum

22

32

6