Table 2 There was a significant difference in Arg25Pro polymorphism between patient and control groups using Yates corrected Chi-square test (p < 0.035). The different distribution at codon 263 failed to be significant, but summarizing the individuals, who were homozygous at both codons, compared with individuals, who where heterozygous either at codon 25 or at codon 263 or at both codons, the difference between the patient and control groups was even more striking (p < 0.015).

From: Analysis of polymorphic TGFB1codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults