Association of HLA class I with severe acute respiratory syndrome coronavirus infection

BMC Medical Genetics

Table 1 HLA-A, B, DRB1 allele typing of 37 probable SARS patients

Case no	HLA-A		HLA-B		HLA-DRB1
1*	2402	3303	4601	5801	0301	0901
2*	0201/07	2402	1525	4601	0901	1202
3*	0201/07	2402	1513	4601	0403/06	1202
4*	1101/02	1101/02	4001	4601	0901	1401/07
5	1101/02	3303	4601	5801	0403/06	0901
6	0201/07	1101/02	4601	5502	0901	0901
7†	1101/02	1101/02	4601	5401	1101/04	1501/02
8	0201/07	2402	4601	1501/12/19	0901	1501/02
9	0201/07	3303	4601	5801	0803	1301/02
10	0203	2402	4601	5201	1001	1602
11	0201/07	3303	4601	4601	0901	1101/04
12	0201/07	1101/02	5201	5401	0405/10	1001
13†	0201/07	2402	5401	5801	0301	0405/10
14	1101/02	2402	1502	5401	0405/10	1401/07
15	0201/07	1101/02	4001	1502	1202	1501/02
16	1101/02	2402	5502	4001	0405/10	0901
17	0203	2402	2704	4001	0403/06	1602
18†	3303	3303	4001	5801	0301	0901
19†	0201/07	1101/02	1511	4001	0901	1602
20	2402	2402	4001	5801	0301	1201
21†	1101/02	1101/02	3901	4001	0403/06	1401/07
22* †	1101/02	2402	4001	8101	0901	1312
23	1101/02	3303	4001	4001	0803	0901
24	2402	3303	3901	5801	0901	1501/02
25	1101/02	1101/02	3901	4803	0803	1405
26†	2402	3303	3901	5801	0301	0901
27†	0203	1101/02	3802	3901	1101/04	1602
28	1101/02	3303	5102	5801	0301	1202
29	1101/02	2402	1502	1502	1202	1202
30	0201/07	1101/02	1301	4001	1401/07	1501/02
31†	0201/07	0301	0702	4601	1101/04	1501/02
32	0301	2402	0702	5502	1401/07	1501/02
33*	0201/07	0201/07	4601	4601	0901	1405
34	0201/07	1101/02	4601	4001	0901	1501/02
35	0201/07	1101/02	5401	1502	0405/10	1401/07
36	0201/07	1101/02	5401	4001	0405/10	1401/07
37	1101/02	1101/02	4001	1502	1401/07	1405

Cases 31 and 32; cases 33 and 34 are mother- daughter pairs. Case 35 is the father of cases 36 and 37 * Fatal cases and one severe respiratory failure patient who survived after intubation (case 33). † Individuals most likely infected by the same probable SARS patient who died 24 hrs after admission.

ISSN: 1471-2350