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Table 5 HLA Haploidentical Alabama Index Cases.1

From: HLA-A and -B alleles and haplotypes in 240 index patients with common variable immunodeficiency and selective IgG subclass deficiency in central Alabama

First Haplotype Second Haplotype Frequency of Haploidentical Index Cases (n)
A*01-B*08 A*02-B*27 0.0154 (3)
  A*02-B*44 0.0256 (5)
  A*03-B*07 0.0205 (4)
  A*23-B*44 0.0103 (2)
  A*29-B*44 0.0103 (2)
  A*30-B*13 0.0103 (2)
  A*32-B*14 0.0103 (2)
A*02-B*07 A*03-B*07 0.0154 (3)
A*02-B*18 A*02-B*44 0.0103 (2)
A*02-B*44 A*02-B*44 0.0205 (4)
  A*02-B*60 0.0103 (2)
  A*03-B*07 0.0205 (4)
  A*03-B*14 0.0103 (2)
  A*25-B*18 0.0103 (2)
  A*31-B*40 0.0103 (2)
A*03-B*07 A*03-B*07 0.0103 (2)
  A*24-B*44 0.0103 (2)
  A*29-B*44 0.0154 (3)
A*24-B*07 A*29-B*18 0.0103 (2)
A*24-B*60 A*28-B*60 0.0103 (2)
  1. 1 These two-haplotype matches were observed in 52 of 195 Caucasian index patients (26.7%) with CVID or IgGSD (390 chromosomes) who resided in central Alabama. Frequencies are expressed as fractions of 195 index cases. Twenty-one patients representing nine different haplotype combination occured in CVID cases, seventeen patients representing six different haplotype combinations occurred in IgGSD cases, and another 14 patients representing seven different haplotype combinations occurred across the the two index patient groups. Evaluation of these data revealed that there were no significant differences in the freqencies of the various haplotypes in these groups of 52 CVID and IgGSD index cases.