HLA-A and -B alleles and haplotypes in 240 index patients with common variable immunodeficiency and selective IgG subclass deficiency in central Alabama

Table 3 Phenotype Frequencies of HLA-B Alleles in Alabama Subjects.¹

B* Phenotypes	Frequency in CVID and IgGSD Index Patients (n = 240)	Frequency in Control Subjects (n)	Significant Uncorrected Values of p	Significant Corrected Values of p ²
07	0.2667	0.2259 (1,321)
08	0.2583	0.2487 (1,315)
13	0.0250	0.0343 (1,314)
14	0.1167	0.0639 (1,314)	0.0037
15	0.0792	0.0144 (1,320)	< 0.0001	< 0.0030
18	0.0708	0.0775 (1,251)
27	0.0708	0.0895 (1,318)
35	0.0917	0.1406 (1,309)	0.0403
37	0.0250	0.0240 (1,167)
38	0.0167	0.0193 (1,194)
39	0.0250	0.0225 (1,198)
40	0.0792	0.0265 (1,321)	< 0.0001	< 0.0030
41	0.0167	0.0119 (1,089)
42	0.0042	0.0040 (1,252)
44	0.3167	0.2866 (1,263)
45	0.0083	0.0177 (1,241)
46	0.0042	0 (19)
47	0.0083	0.0039 (513)
48	0.0042	0 (909)
49	0.0417	0.0171 (1,230)	0.0153
50	0.0333	0.0140 (1,212)	0.0414
51	0.1042	0.0696 (1,250)
52	0.0167	0.0180 (1,164)
53	0.0083	0.0077 (1,163)
54	0	0.0058 (1,027	- - -
55	0.0208	0.0259 (1,042)
56	0.0125	0.0097 (928)
57	0.0667	0.0385 (1,014)
58	0.0042	0.0256 (1,014)	0.0228
60	0.0583	0.1206 (1,086)
61	0.0167	0.0173 (980)
62	0.0333	0.1285 (1,175)	< 0.0001	< 0.0030
78	0.0042	no data	- - -

¹ Phenotypes were detected using low-resolution DNA-based typing in CVID and IgGSD patients and microlymphocytotoxcity typing in control subjects. ²These values were corrected using the Bonferroni inequality method.

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