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Table 1 Allele frequency of the 77C→G transition in PTPRC. Homozygosity was not observed.

From: PTPRC(CD45) is not associated with multiple sclerosis in a large cohort of German patients

 

C allele (%)

G allele (%)

Controls (N = 347)

684 (98.6)

10 (1.4)

MS patients (N = 454)

901 (99.2)

7 (0.8)*

RRMS (N = 219)

435 (99.3)

3 (0.7)

SPMS (N = 92)

182 (98.9)

2 (1.1)

PPMS (N = 70)

139 (99.3)

1 (0.7)

HLA-DRB1 * 15 MS patients (N = 161)

320 (99.4)

2 (0.6)

  1. * p = 0.2. RRMS = relapsing remitting course of MS; SPMS = secondary progressive course of MS; PPMS = primary progressive course of MS