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Table 2 Distributionof APOE genotypes and alleles in the case-control association study

From: Apolipoprotein E gene polymorphism is not a strong risk factor for diabetic nephropathy and retinopathy in Type I diabetes: case-control study

  Type I Type I P Type I Type I P
  diabetes diabetes value diabetes diabetes Value
  subjects subjects   subjects subjects  
  with without   with without  
  nephropathy nephropathy   retinopathy retinopathy  
  (DN+) (DN-)   (DR+) (DR-)  
  n (%) n (%)   n (%) n (%)  
  m/f (%/%) m/f (%/%)   m/f (%/%) m/f (%/%)  
  74 (100) 92(100)   76 (100) 96(100)  
Total subjects 40/34 40/52   34/42 50/46  
  (54.0/46.0) (43.5/56.5)   (44.7/55.3) (52.1/47.9)  
   2(2.2)    1(1.0)  
E2E2 0 0/2 NS 0 0/1 NS
   (0/3.8)    (0/2.2)  
  48(64.9) 54(58.7)   45(59.2) 61(63.6)  
E3E3 25/23 27/27 NS 21/24 33/28 NS
  (62.5/67.6) (67.5/51.9)   (61.8/57.1) (66.9/60.9)  
      1(1.0)  
E4E4 0 0 NS 0 0/1 NS
      (0/2.2)  
  13(17.6) 20(21.7)   18(23.7) 16(16.7)  
E2E3 8/5 5/15 NS 9/9 6/10 NS
  (20.0/14.7) (12.5/28.8)   (26.4/21.4) (12.0/21.7)  
  3(4.0)    3(3.9) 1(1.0)  
E2E4 0/3 0 NS 0/3 1/0 NS
  (0/8.9)    (0/7.2) (2.0/0)  
  10(13.5) 16(17.4)   10(13.2) 16(16.7)  
E3E4 7/3 8/8 NS 4/6 10/6 NS
  (17.5/8.8) (20.0/15.5)   (11.8/14.3) (20.0/13.0)  
  16(10.8) 24(13.0)   21(13.8) 19(9.9)  
E2 8/8 5/19 NS 9/12 7/12 NS
  (10.0/11.8) (6.3/18.3)   (13.2/14/3) (7.0/13.0)  
  119(80.4) 144(78.3)   118(77.6) 154(80.2)  
E3 65/54 67/77 NS 55/63 82/72 NS
  (81.3/79.4) (83.7/74.0)   (80.9/75.0) (82.0/78.3)  
  13(8.8) 16(8.7)   13(8.6) 19(9.9)  
E4 7/6 8/8 NS 4/9 11/8 NS
  (8.7/8.8) (10.0/7.7)   (5.9/10.7) (11.0/8.7)  
Total 148 (100) 184(100)   152(100) 192(100)  
chromosomes 80/68 40/104   68/84 100/92  
  (54.1/45.9) (43.5/56.5)   (44.7/55.3) (52.1/47.9)  
  1. NS, not significant (P value > 0.05)