| GAD65-positive | GAD65-negative | Controls |
---|
| T1DM | T1DM | |
---|
| n = 48 | n = 30 | n = 250 |
---|
Genotype frequenciesa
| | | |
FF | 26 (54%) | 10(33%) | 82 (33%) |
Ff | 19 (40%) | 18(60%) | 138 (55%) |
ff | 3(6%) | 2(7%) | 30 (12%) |
Allele frequenciesb
| | | |
F | 71 (74%) | 38(63%) | 302(60%) |
f | 25 (26%) | 22(37%) | 198(40%) |
Phenotype frequenciesc
| | | |
F positive | 45 (94%) | 28 (94%) | 220(88%) |
f positive | 22 (46%) | 20 (67%) | 168(67%) |
- Values shown are the number of subjects with the percentage in parentheses. aΧ2 test of heterogeneity between GAD65-positive T1DM patients and control subjects. Χ2 = 8.14, 2 degrees of freedom; P = 0.017. bΧ2 test of heterogeneity between GAD65-positive T1DM patients and control subjects. Χ2 = 6.32, 1 degree of freedom; P = 0.012. cRelative risk ratio for F phenotype (GAD65-positive T1DM) = 2.0.