| |
GAD65-positive
|
GAD65-negative
|
Controls
|
|---|
| |
T1DM
|
T1DM
| |
|---|
| |
n = 48
|
n = 30
|
n = 250
|
|---|
|
Genotype frequenciesa
| | | |
|
FF
|
26 (54%)
|
10(33%)
|
82 (33%)
|
|
Ff
|
19 (40%)
|
18(60%)
|
138 (55%)
|
|
ff
|
3(6%)
|
2(7%)
|
30 (12%)
|
|
Allele frequenciesb
| | | |
|
F
|
71 (74%)
|
38(63%)
|
302(60%)
|
|
f
|
25 (26%)
|
22(37%)
|
198(40%)
|
|
Phenotype frequenciesc
| | | |
|
F positive
|
45 (94%)
|
28 (94%)
|
220(88%)
|
|
f positive
|
22 (46%)
|
20 (67%)
|
168(67%)
|
- Values shown are the number of subjects with the percentage in parentheses. aΧ2 test of heterogeneity between GAD65-positive T1DM patients and control subjects. Χ2 = 8.14, 2 degrees of freedom; P = 0.017. bΧ2 test of heterogeneity between GAD65-positive T1DM patients and control subjects. Χ2 = 6.32, 1 degree of freedom; P = 0.012. cRelative risk ratio for F phenotype (GAD65-positive T1DM) = 2.0.
