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Table 1 General characteristics of the Study Subjects

From: Platelet count and Interleukin 6 Gene polymorphism in healthy subjects

Variable

C/C

G/C and GG

P

N

15

44

-

Men/women

8/7

26/18

NS

Age (years)

36.4 ± 10.6

40.4 ± 8.5

NS

Body mass index

26.07 ± 5.1

26.8 ± 4.8

NS

(Kg/m2)

   

Smokers (yes/no)

4/11

12/32

NS

Platelet count (/μl)

205400 ± 44088

239818 ± 60194a

0.04

Median (range)

201.000 (135000-298000)b

223.500 (159000-477000)c

 

WBC (× 109/ml)

5807 ± 1671

6867 ± 1192

0.01

Hematocrit (%)

40.4 ± 5.4

42.2 ± 4.8

NS

Circulating IL-6 (pg/ml)*

6.8 ± 1.7

10.3 ± 6.9

0.07

  1. C/C, C/G and G/G define the allele polymorphism of the promoter of interleukin-6 gene. Data are provided as mean ± SD. * IL-6, circulating interleukin 6, which was determined in 30 subjects, 10 of whom with the C/C allele; WBC, peripheral white blood cells. a. After excluding the outlier, the differences remained significant at a p = 0.046. b. There was only one subject below the lower normal range of 150.000 platelets/μl and 6 between 160.000-185.000/μl. c. The maximum platelet level is 353.000/μl after excluding the outlier. The normal range, mean and median of platelet counts are 230.970, 220500 (150.000-400.000) /ml.