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Table 1 General characteristics of the Study Subjects

From: Platelet count and Interleukin 6 Gene polymorphism in healthy subjects

Variable C/C G/C and GG P
N 15 44 -
Men/women 8/7 26/18 NS
Age (years) 36.4 ± 10.6 40.4 ± 8.5 NS
Body mass index 26.07 ± 5.1 26.8 ± 4.8 NS
(Kg/m2)    
Smokers (yes/no) 4/11 12/32 NS
Platelet count (/μl) 205400 ± 44088 239818 ± 60194a 0.04
Median (range) 201.000 (135000-298000)b 223.500 (159000-477000)c  
WBC (× 109/ml) 5807 ± 1671 6867 ± 1192 0.01
Hematocrit (%) 40.4 ± 5.4 42.2 ± 4.8 NS
Circulating IL-6 (pg/ml)* 6.8 ± 1.7 10.3 ± 6.9 0.07
  1. C/C, C/G and G/G define the allele polymorphism of the promoter of interleukin-6 gene. Data are provided as mean ± SD. * IL-6, circulating interleukin 6, which was determined in 30 subjects, 10 of whom with the C/C allele; WBC, peripheral white blood cells. a. After excluding the outlier, the differences remained significant at a p = 0.046. b. There was only one subject below the lower normal range of 150.000 platelets/μl and 6 between 160.000-185.000/μl. c. The maximum platelet level is 353.000/μl after excluding the outlier. The normal range, mean and median of platelet counts are 230.970, 220500 (150.000-400.000) /ml.