|
Group
|
Allele frequency n (%)
|
Genotype frequency n (%)
|
|---|
| |
Ala
|
Val
|
Ala/Ala
|
Ala/Val
|
Val/Val
|
|---|
|
Neuropathy (n = 82)
|
83a (50.6)
|
81b (49.4)
|
14c (17.1)
|
55 (67.0)
|
13d (15.9)
|
|
No neuropathy (n = 84)
|
115 (68.5)
|
53 (31.5)
|
33 (39.3)
|
49 (58.3)
|
2 (2.4)
|
-
a Ala allele frequency was significantly lower in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 0.48, p = 0.00067, pc = 0.00134). b Val allele frequency was significantly higher in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 2.10, p = 0.00067, pc = 0.00134). c Ala/Ala genotype frequency was significantly lower in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 0.34, p = 0.00122, pc = 0.00366). d Val/Val genotype frequency was significantly higher in patients with diabetic neuropathy tha in subjects without this complication (odds ratio = 5.10, p = 0.00219, pc = 0.00657).
