Skip to main content

Table 3 Models used in the analysis with penetrance classes by diagnostic class (D = disease allele)

From: Linkage analysis of HLA and candidate genes for celiac disease in a North American family-based study

 

Model

Diagnosis

      
 

dd

Dd

DD

   
 

Dominant model (disease allele frequency = 0.0001)

Biopsy or EMA+

0.001

0.5

0.5

   

Unknown/unaffected

0.001

0.001

0.001

   
 

Recessive model (disease allele frequency = 0.01)

Biopsy or EMA+

0.001

0.001

0.5

   

Unknown/unaffected

0.001

0.001

0.001

   
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us