|
Total subjects
| |
---|
|
GG
|
GA + AA
|
p-value
|
---|
|
(n. = 145)
|
(n = 49)
| |
---|
Age (yrs)
|
48.9 ± 1.3
|
49.4 ± 1.8
|
NS
|
Body Mass Index (kg/m2)
|
31.6 ± 0.6
|
29.1 ± 0.7
|
<0.05*
|
Blood glucose (mmol/L)
|
5.06 ± 01
|
4.79 ± 0.2
|
NS
|
Fasting plasma insulin (μU/ml)
|
18.9 ± 1.5
|
21.4 ± 3.8
|
NS
|
HOMA IIR
|
4.34 ± 0.3
|
4.79 ± 0.2
|
NS
|
Plasma lipids (mmol/L)
| | | |
Total cholesterol
|
219.0 ± 4.4
|
214.4 ± 6.8
|
NS
|
Total triglycerides
|
154.2 ± 11.4
|
156.1 ± 15.6
|
NS
|
HDL cholesterol
|
48.5 ± 1.4
|
47.2 ± 2.8
|
NS
|
LDL cholesterol
|
132.5 ± 4.1
|
127.3 ± 7.1
|
NS
|
- Data are given as means ± SEM. All p-values were corrected for differences in age GG, GA, and AA = TNF-α genotypes. * p-value after correction = not significant. The statistical analysis of total triglycerides and plasma insulin were performed on log-trasformed values, but the untrasformed values are given in table. Continuous variables were compared by t-test and categorical variables by Χ2 test.