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Table 1 Clinical characteristics of study subjects

From: The G-308A variant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution

  Obese subjects Lean subjects p-value
  (n = 115) (n = 79)  
Age (yrs) 47.04 ± 1.3 51.36 ± 1.8 P < 0.01
Sex (M/F) 37 / 78 27/52 NS
BMI (kg/m2) 33.93 ± 0.512 24.30 ± 0.313 <0.0001
Blood glucose (mg/dl) 91.56 ± 2.0 86.84 ± 10.08 NS
Fasting plasma insulin (μU/ml) 22.72 ± 1.7 9.29 ± 1.04 <0.0001
HOMAIR 5 ± 0.16 2.2 ± 0.45 <0.0003
Plasma lipids (mg/dL)    
   Total cholesterol 218.69 ± 4.5 214.95 ± 6.1 NS
   HDL cholesterol. 48.16 ± 1.4 48.2 ± 2.2 NS
   Total triglycerides 156.85 ± 12.5 157.26 ± 12.96 NS
   LDL cholesterol 128.61 ± 5.1 131.2 ± 5 NS
  1. Data are given as means ± SEM. All p-values were corrected for differences in age The statistical analysis of total triglycerides and plasma insulin were performed on log-trasformed values, but the untrasformed values are given in table. Continuous variables were compared by t-test and categorical variables by Χ2 test.