| |
Obese subjects
|
Lean subjects
|
p-value
|
|---|
| |
(n = 115)
|
(n = 79)
| |
|---|
|
Age (yrs)
|
47.04 ± 1.3
|
51.36 ± 1.8
|
P < 0.01
|
|
Sex (M/F)
|
37 / 78
|
27/52
|
NS
|
|
BMI (kg/m2)
|
33.93 ± 0.512
|
24.30 ± 0.313
|
<0.0001
|
|
Blood glucose (mg/dl)
|
91.56 ± 2.0
|
86.84 ± 10.08
|
NS
|
|
Fasting plasma insulin (μU/ml)
|
22.72 ± 1.7
|
9.29 ± 1.04
|
<0.0001
|
|
HOMAIR
|
5 ± 0.16
|
2.2 ± 0.45
|
<0.0003
|
|
Plasma lipids (mg/dL)
| | | |
|
Total cholesterol
|
218.69 ± 4.5
|
214.95 ± 6.1
|
NS
|
|
HDL cholesterol.
|
48.16 ± 1.4
|
48.2 ± 2.2
|
NS
|
|
Total triglycerides
|
156.85 ± 12.5
|
157.26 ± 12.96
|
NS
|
|
LDL cholesterol
|
128.61 ± 5.1
|
131.2 ± 5
|
NS
|
- Data are given as means ± SEM. All p-values were corrected for differences in age The statistical analysis of total triglycerides and plasma insulin were performed on log-trasformed values, but the untrasformed values are given in table. Continuous variables were compared by t-test and categorical variables by Χ2 test.
