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Table 2 The adjusted odd ratios between asthma status and the CHI3L1 polymorphisms rs1538372 and rs10399931 according to three inheritance modes

From: CHI3L1polymorphisms associate with asthma in a Taiwanese population

Categories

Case/Control

OR (95% CI)

aOR (95% CI)a

rs1538372

   

  Co-dominant genotype

   

   TT

65/90

1

1

   TC

293/312

1.3 (0.91–1.86)

1.54 (0.98–2.43)

   CC

270/226

1.65 (1.15–2.38)

1.97 (1.23–3.14)

  Recessive genotype

   

   TT + TC

358/402

1

1

   CC

270/226

1.34 (1.07–1.68)

1.39 (1.04–1.86)

  Dominant genotype

   

   TT

65/90

1

1

   TC + CC

563/538

1.45 (1.03–2.04)

1.72 (1.11–2.66)

rs10399931

   

  Co-dominant genotype

   

   AA

72/90

1

1

   GA

286/307

1.16 (0.82–1.65)

1.36 (0.88–2.10)

   GG

270/229

1.47 (1.03–2.11)

1.77 (1.13–2.77)

  Recessive genotype

   

   AA + GA

358/397

1

1

   GG

270/229

1.31 (1.04–1.64)

1.39 (1.04–1.86)

Dominant genotype

   

   AA

72/90

1

1

   GA + GG

556/536

1.30 (0.93–1.81)

1.53 (1.01–2.32)

  1. aAdjusted odds ratio and 95% confidence intervals (aOR and 95% CI) are shown using multiple logistic regressions to control variables, including sex, age, BMI, logIgE, smoking, pet exposure, indoor incense burning, and parents’ asthma history.