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Table 3 Jaccard distance between pairs of disorders associated to genes influencing tobacco use disorder

From: Genetic similarities between tobacco use disorder and related comorbidities: an exploratory study

Disorder Addiction Alcoholism Bladder cancer Coronary disease Depressive disorder Gastric cancer Malignant hypertension Motor dysfunction Oesophageal cancer Psychomotor agitation Schizoaffective disorder Schizophrenia Stroke Tobacco used disorder
Alcoholism 0.138              
Bladder cancer 0.448 0.360             
Coronary disorder 0.367 0.269 0.200            
Depressive disorder 0.133 0.074 0.407 0.259           
Gastric cancer 0.345 0.370 0.158 0.304 0.414          
Malignant hypertension 0.448 0.360 0.000 0.200 0.407 0.158         
Motor dysfunction 0.310 0.269 0.200 0.261 0.321 0.227 0.200        
Oesophageal cancer 0.448 0.360 0.000 0.200 0.407 0.158 0.000 0.200       
Psychomotor agitation 0.379 0.280 0.111 0.190 0.333 0.238 0.111 0.100 0.111      
Schizoaffective disorder 0.138 0.000 0.360 0.269 0.074 0.370 0.360 0.269 0.360 0.280     
Schizophrenia 0.161 0.107 0.429 0.286 0.103 0.433 0.429 0.345 0.429 0.357 0.107    
Stroke 0.241 0.192 0.273 0.174 0.250 0.292 0.273 0.091 0.272 0.182 0.192 0.276   
Tobacco use disorder 0.103 0.241 0.384 0.413 0.233 0.269 0.385 0.296 0.384 0.370 0.241 0.258 0.345  
Vascular disorder 0.258 0.214 0.360 0.200 0.207 0.370 0.360 0.200 0.360 0.280 0.214 0.172 0.120 0.355
  1. Colours representing the genetic similarities between disorders: bold = strong similarities (<0.15); italic = middle similarities (0.15-0.35); normal = low similarities (>0.35).