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Table 3 Jaccard distance between pairs of disorders associated to genes influencing tobacco use disorder

From: Genetic similarities between tobacco use disorder and related comorbidities: an exploratory study

Disorder

Addiction

Alcoholism

Bladder cancer

Coronary disease

Depressive disorder

Gastric cancer

Malignant hypertension

Motor dysfunction

Oesophageal cancer

Psychomotor agitation

Schizoaffective disorder

Schizophrenia

Stroke

Tobacco used disorder

Alcoholism

0.138

             

Bladder cancer

0.448

0.360

            

Coronary disorder

0.367

0.269

0.200

           

Depressive disorder

0.133

0.074

0.407

0.259

          

Gastric cancer

0.345

0.370

0.158

0.304

0.414

         

Malignant hypertension

0.448

0.360

0.000

0.200

0.407

0.158

        

Motor dysfunction

0.310

0.269

0.200

0.261

0.321

0.227

0.200

       

Oesophageal cancer

0.448

0.360

0.000

0.200

0.407

0.158

0.000

0.200

      

Psychomotor agitation

0.379

0.280

0.111

0.190

0.333

0.238

0.111

0.100

0.111

     

Schizoaffective disorder

0.138

0.000

0.360

0.269

0.074

0.370

0.360

0.269

0.360

0.280

    

Schizophrenia

0.161

0.107

0.429

0.286

0.103

0.433

0.429

0.345

0.429

0.357

0.107

   

Stroke

0.241

0.192

0.273

0.174

0.250

0.292

0.273

0.091

0.272

0.182

0.192

0.276

  

Tobacco use disorder

0.103

0.241

0.384

0.413

0.233

0.269

0.385

0.296

0.384

0.370

0.241

0.258

0.345

 

Vascular disorder

0.258

0.214

0.360

0.200

0.207

0.370

0.360

0.200

0.360

0.280

0.214

0.172

0.120

0.355

  1. Colours representing the genetic similarities between disorders: bold = strong similarities (<0.15); italic = middle similarities (0.15-0.35); normal = low similarities (>0.35).