Skip to main content

Table 1 Genes associated to tobacco use disorder selected from Gene2Mesh and Ingenuity

From: Genetic similarities between tobacco use disorder and related comorbidities: an exploratory study

Gene Gene function Gene2Mesh Ingenuity
CHAT Nicotinic receptor X  
CHRNA1 Nicotinic receptor   X
CHRNA2 Nicotinic receptor   X
CHRNA3 Nicotinic receptor X X
CHRNA4 Nicotinic receptor X X
CHRNA5 Nicotinic receptor X X
CHRNA6 Nicotinic receptor   X
CHRNA7 Nicotinic receptor   X
CHRNA9 Nicotinic receptor   X
CHRNA10 Nicotinic receptor   X
CHRNB1 Nicotinic receptor   X
CHRNB2 Nicotinic receptor   X
CHRNB3 Nicotinic receptor   X
CHRNB4 Nicotinic receptor   X
CHRND Nicotinic receptor   X
CHRNE Nicotinic receptor   X
CHRNG Nicotinic receptor   X
COMT Dopamine X  
CYP2A6 Nicotine metabolism X  
DDC Dopamine X X
DRD2 Dopamine X  
GABBR2 GABA   X
GABRA2 GABA X  
GABRA4 GABA X  
NRXN1 Neurexin   X
OPRD1 Opioid receptor   X
OPRM1 Opioid receptor   X
OPRK1 Opioid receptor   X
SIGMAR1 Non-opioid receptor   X
SLC6A3 Dopamine X X
SLC6A4 Serotonin X X
TPH1 Serotonin X  
  1. Selected genes are represented by X; GABA, Gamma-aminobutyric acid.