Skip to main content

Table 2 The top 10 most significantly up- or down-regulated DEGs

From: Meta-analysis of differentially expressed genes in osteosarcoma based on gene expression data

Gene ID

Gene symbol

P-value

Fold change

Official full name

Up-regulated genes

Ā Ā 

1363

CPE

5.08E-15

3.856

Carboxypeptidase E

23462

HEY1

6.72E-15

2.7097

Hes-related family bHLH transcription factor with YRPW motif 1

5538

PPT1

8.34E-15

2.7668

Palmitoyl-protein thioesterase 1

58155

PTBP2

2.19E-12

1.7278

Polypyrimidine tract binding protein 2

81035

COLEC12

3.87E-12

1.7098

Collectin sub-family member 12

54504

CPVL

4.90E-12

2.4601

Carboxypeptidase, vitellogenic-like

53826

FXYD6

2.40E-11

2.3862

FXYD domain containing ion transport regulator 6

54453

RIN2

5.85E-11

1.6714

Ras and Rab interactor 2

80135

RPF1

5.94E-11

1.7889

Ribosome production factor 1 homolog (S. cerevisiae)

1942

EFNA1

1.23E-10

1.9501

Ephrin-A1

Down-regulated genes

Ā Ā 

4883

NPR3

1.9E-48

āˆ’2.352

Natriuretic peptide receptor 3

25802

LMOD1

4.1E-32

āˆ’1.5799

Leiomodin 1 (smooth muscle)

2621

GAS6

2.5E-31

āˆ’2.6934

Growth arrest-specific 6

5959

RDH5

4.2E-30

āˆ’2.3838

Retinol dehydrogenase 5 (11-cis/9-cis)

316

AOX1

3.2E-28

āˆ’2.1826

Aldehyde oxidase 1

55679

LIMS2

9.2E-28

āˆ’1.7498

LIM and senescent cell antigen-like domains 2

4053

LTBP2

7.3E-27

āˆ’3.0523

Latent transforming growth factor beta binding protein 2

5999

RGS4

8.3E-27

āˆ’3.2551

Regulator of G-protein signaling 4

8613

PPAP2B

2.2E-25

āˆ’2.6475

Phosphatidic acid phosphatase type 2B

23529

CLCF1

6.5E-25

āˆ’1.6977

Cardiotrophin-like cytokine factor 1