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Table 3 Frequency of CYP3A4 and CYP3A5 polymorphisms in 20 HIV-infected patients

From: Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs

Genotype/20 pts
Gene Polymorphism wt ( n. pts) m ( n. pts)
CYP3A4    
  CYP3A4*1B; 816 A > G 5′-flanking region 17/20 3
  CYP3A4*2; 15831 T < C exon 7 20  
  CYP3A4*4; 13989 A > G exon 5 20  
  CYP3A4*5; 15820 C > G exon 7 20  
  CYP3A4*6; 17775 insA exon 9 20  
  CYP3A4*8; 14026 G > A exon 5 20  
  CYP3A4*11; 21973 C > T exon 11 20  
  CYP3A4*12; 22002 C > T exon 11 20  
  CYP3A4*13; 22132 C > T exon 11 20  
  CYP3A4*16; 15721 C > G exon 7 20  
  CYP3A4*17; 15733 T > C exon 7 20  
  CYP3A4*18; 20178 T > C exon 10 20  
CYP3A5    
  CYP3A5*3; 12083 G > A intron 3 17/20 3
  CYP3A5*5; 18049 T > C intron 5 20  
  CYP3A5*6; 19787 G > A exon 7 20  
  CYP3A5*8; 8801 C > T exon 2 20  
  CYP3A5*9; 24483 G > A exon 10 20  
  CYP3A5*10; 34850 T > C exon 12 20  
  1. Wt: wild-type, m: mutated.