|
CYP3A4 gene
| | | | | |
|
A
|
5′ Proximal Region
|
A1: GGTCTGTCTGTCTGGGTATGC
| |
296
|
61
|
| | |
A2: CTCACCACACACTGACCTGCT
| | | |
|
B
|
EXON 1 (nt 1–71)
|
B1: AGAACCCAGAACCCTTTGGAC
|
1
|
1137
|
59
|
| | |
B2: GTGCTCCTCTATCTGTGAGTA
|
78
| | |
|
C
|
EXON 2 (nt 4004–4097)
|
C1: GCTCTCAGTGACCCTCTGTG
|
3532
|
1192
|
59
|
| | |
C2: AACCCCTTTGTTCTGTCTCTCA
|
4723
| | |
|
D
|
EXON 3 (nt 6009–6061)
|
D1: CCCTGGTGTCTGTACTTTCCA
|
5529
|
1200
|
59
|
| | |
D2: TCCCAGCCTAGTTCAGACTGT
|
6728
| | |
|
E
|
EXON 4 (nt 11502–11601)
|
E1: ATATCCACGTATGCACCACCC
|
11185
|
841
|
59
|
| | |
E2: GAGCCACATGGAGACAGAGT
|
12025
| | |
|
F
|
EXONS 5/6 (nt 13956–14069) (nt 14335−14423)
|
F1: CGACATCAGGGTCTCCTGAAC
|
13720
|
933
|
59
|
| | |
F2: GATATGTAAACCCTGGCCCCT
|
14652
| | |
|
G
|
EXON 7 (nt 15689–15837)
|
G1: CTGTTTGTCTGTCTTGACTGGA
|
15585
|
998
|
61
|
| | |
G2: GCTGTTCAAGAAATAGTAGGTAGTC
|
16582
| | |
|
H
|
EXON 8 (nt 16932–17059)
|
H1: TTGAGCTTCAGATTATGATTTGGG
|
16593
|
956
|
60
|
| | |
H2: CTGGCTATCATGTGAGATGGC
|
17548
| | |
|
I
|
EXON 9 (nt 17744–17810)
|
I1: AGCCATCTCACATGATAGCCA
|
17527
|
990
|
57
|
| | |
I2: CTTGGTGGCTTGTAATTGACC
|
18516
| | |
|
J
|
EXON 10 (nt 20166–20326)
|
J1: TGGGGGAGAGTACTACCTCATA
|
19785
|
952
|
60
|
| | |
J2: AAGAGCCAATTCCTGTGTCCAT
|
20736
| | |
|
K
|
EXON11 (nt 21912–22138)
|
K1: TTCCCGAATGCTTCCCACCT
|
21691
|
917
|
59
|
| | |
K2: ATGCTACTGTACCGATGTAATGC
|
22607
| | |
|
L
|
EXON 12 (nt 23198–23360)
|
L1: GGGGTGGCCCCTAAGTAAGA
|
23109
|
910
|
57
|
| | |
L2: TTGGGTTGAAAAGGAGCCCA
|
24018
| | |
|
M
|
EXON 13 (nt 25950–26502)
|
M1: TGACTCTTCAAAAACAGTTTGCCA
|
25518
|
1099
|
59
|
| | |
M2: AGTTCTGACAAAGGCCCCAC
|
26502
| | |
|
CYP3A5 gene
| | | | | |
|
N
|
EXON 1 (5001–5173)
|
N1: TAGAATGAAGGCAGCCATGGAG
|
4723
|
1032
|
60
|
| | |
N2: GGGGATTTTCAGGGGCATGG
|
5774
| | |
|
O
|
EXON 2 (8791–8884)
|
O1: GCTGGTTCTTCTGCACACAATC
|
8022
|
964
|
61
|
| | |
O2: GAAACCTCAGAACTCCCTCCC
|
8985
| | |
|
P
|
EXON 3 (10414–10466)
|
P1: ATGGAGAGTGGCATAGGAGAT
|
9878
|
1177
|
59
|
| | |
P2: TGTGGTCCAAACAGGGAAGAGAT
|
11054
| | |
|
Q
|
EXON 4 (12320–12419)
|
Q1: TGTCACCAGGTATCGAGGTCT
|
11062
|
1367
|
60
|
| | |
Q2: GATGCTTACCCTTCGATTTGTGA
|
12428
| | |
|
R
|
EXONS 5/6 (17934–18047) (18310–18398)
|
R1: CGCCCCACATACACTCAGAA
|
17746
|
1184
|
57
|
| | |
R2: GGCTTGCTCTACACATAGCAT
|
18929
| | |
|
S
|
EXON 7 (19685–19833)
|
S1: ATAGGGCCAGCTCCATCACTG
|
19492
|
1193
|
60
|
| | |
S2: TTCTGAGTCTTTGGAGTGACCA
|
20684
| | |
|
T
|
EXONS 8/9 (20904–21031) (22117–22183)
|
T1: GGCCTGAAAGAAGGGCAAAC
|
20750
|
1478
|
57
|
| | |
T2: TCTTAGTGTCCCCGCCAGTA
|
22228
| | |
|
U
|
EXON 10 (24340–24500)
|
U1: AGGATCATTCAAGGCACACACC
|
24009
|
1179
|
61
|
| | |
U2: GCCTTGCTGCTGCCTTGCAG
|
25188
| | |
|
V
|
EXON 11 (32220–32446)
|
V1: ACCTACCTATGATGCCGTGG
|
32225
|
880
|
57
|
| | |
V2: GAGGACCTGTGCTGTCTTGT
|
33104
| | |
|
W
|
EXON 12 (34767–34926)
|
W1: GCAGGATTTCAATGACCAGCC
|
34619
|
1173
|
59
|
| | |
W2: CCCCCTGCCTGAATACACAC
|
35792
| | |
|
Y
|
EXON 13 (36599–36809)
|
Y1: GGGTTCAACTGGGAAGGGTT
|
36118
|
1058
|
57
|
| | |
Y2: GTGTGCAGGATGGCATCAGA
|
37175
| | |
