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Table 1 Clinical symptoms and results of mutation analysis of the two families

From: A novel insertion mutation identified in exon 10 of the MEFV gene associated with Familial Mediterranean Fever

Family

Relation

Gender, age (year)

Age of symptoms onset

Exon 10 mutation type

Common FMF symptoms

Abd. pain

Fever

Chest pain

Arthritis

Skin lesions

Amyloidosis

Family A

Father

M, 41y

No Sx*

wt**

-

-

-

-

-

-

 

Mother

F, 35y

30y

c.2330dupG/0

+

+

-

-

-

-

 

Child 11

M, 16y

15y

c.2330dupG/0

+

+

-

+

-

-

 

Child 2

F, 10y

No Sx

wt**

-

-

-

-

-

-

Family B

Father

M, 35y

No Sx

V726A/0

-

-

-

-

-

-

 

Mother

F, 32y

20y

c.2330dupG/M694V

+

+

+

-

-

-

 

Child 11

M, 7y

6y

c.2330dupG/0

+

+

-

-

-

-

 

Child 2

M, 10y

3y

M694V/V726A

+

+

-

-

-

-

  1. No Sx*: No Symptoms; wt**: Wild type; 1: Probands.