Figure 3
From: Five novel mutations in the ADAR1 gene associated with dyschromatosis symmetrica hereditaria
Aberrant splicing pattern of ADAR1 caused by c.1601G > A mutation. (A) Locations of primers used in RT-PCR; (B) RT-PCR analysis revealed a transcript abnormality in ADAR1; (C) cDNA sequencing and predicted amino acid sequence of the aberrant (left) and normal (right) transcripts of ADAR1; (D) The relative quantities of ADAR1 mRNA level derived from real-time quantitative RT-PCR.