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Table 1 Clinical features and detected mutations of OI patients

From: COL1A1and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients

Clinical data MOOI-I 1 MOOI-III 2 MOOI-III 3 MOOI-I 4
OI Type*1 I III III I
Gender M F M F
Age (years) 26 23 15 41
Family history No No No No
Number of fractures + 30 + 30 + 30 − 30
Bone deformities Yes Yes Yes Yes
Blue sclera Yes Yes Yes Yes
Dentinogenesis imperfecta Yes Yes Yes Yes
Hearing loss No No Yes Yes
Mutation COL1A1 c.3076C > T, Arg1026X COL1A2 c.2503G > A, Gly835Ser COL1A1 c. 869G > A, Gly290Glu COL1A1 c.198_204dupCAAGGTG, Leu69Glu-fsX74
  1. *1According to Sillence et al. [2].