Table 2 Analysis of genetic effect of ALDH2 Glu487Lys on risk of TB (n = 1,273)
From: Functional polymorphism in aldehyde dehydrogenase-2 gene associated with risk of tuberculosis
Genotype | TB | Control | Referent analysisa | Co-dominant model | Dominant model | Recessive model | ||||
|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
Glu/Glu | 391(82%) | 559(70.2%) | 1 | - | ||||||
Glu/Lys | 78(16.4%) | 216(27.1%) | 0.52 (0.39-0.69) | 0.000008 | 0.57 (0.45-0.74) | 0.00001 | 0.52 (0.39-0.69) | 0.000004 | 0.63 (0.28-1.43) | 0.27 |
Lys/Lys | 8(1.7%) | 21(2.6%) | 0.55 (0.24-1.24) | 0.15 | ||||||