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Table 3 Logistic regression model (outcome variable: systolic blood pressure ≥160 mmHg and/or taking antihypertensive drugs)

From: Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study

 

n

OR

95% CI

P

   

Lower

Upper

 

rs4606 genotype (unadjusted)

2944

    

 CG

 

1.03

0.81

1.31

0.834

 GG

 

1.02

0.66

1.60

0.921

Minimally adjusted model #

2936

    

rs4606 genotype

     

 CG

 

1.00

0.76

1.32

0.978

 GG

 

1.16

0.69

1.93

0.582

Multivariate model

2123

    

rs4606 genotype

     

 CG

 

1.38

0.96

1.99

0.083

 GG

 

1.88

1.02

3.47

0.044*

Main effects model §

2211

    

rs4606 genotype

     

 CG

 

1.36

0.96

1.92

0.088

 GG

 

1.93

1.05

3.53

0.033*

History of preeclampsia vs. control

 

3.27

2.32

4.60

<0.001*

Age

 

1.13

1.11

1.15

<0.001*

Hard Physical activity

 

0.58

0.39

0.88

0.010*

BMI ≥ 25

 

2.38

1.60

3.53

0.001*

Diabetes

 

5.14

2.31

11.4

<0.001*

  1. *Statistically significant P < 0.05. ‡Reference: CC genotype. #Age and BMI from HUNT2 and a history of preeclampsia were included in the minimally adjusted model in addition to the rs4606. †In addition to the rs4606, a history of preeclampsia and the following variables from HUNT2 were included in the multivariate model: age, CVD ever (= a current or past diagnosis of angina pectoris, myocardial infarction or cerebral stroke; Yes/No), Diabetes ever (Yes/No), Smoking cigarettes (Yes/No), Number of children (≥ 2 vs. 1), Hard physical activity (≥ 1 h/week vs. <1 h/week), BMI, Total Cholesterol/HDL-ratio. §Main effects model includes only variables significant at P < 0.05. BMI = Body mass index.