From: Polymorphisms in the glutathione pathway modulate cystic fibrosis severity: a cross-sectional study
CFTRgroup | PI taking into account | Haplotype | Genotype | Variable | pc | OR | CI (5–95%) | ||
---|---|---|---|---|---|---|---|---|---|
AX | |||||||||
Presence | Absence | Total | |||||||
Two mutation identified | No | GCLC-129C > T + GCLC-3506A > G | CC + AA | 10 | 26 | 36 | 17.9 | 2.781-411.6 | |
CC + (AG or GG) | 1 | 30 | 31 | 0.024 | 0.149 | 0.007-0.959 | |||
(CT or TT) + GG | 0 | 13 | 13 | - | - | ||||
TT + GG | 0 | 5 | 5 | - | - |