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Table 2 Distribution of individual genotypes among CT (+) and CT (-) tumors

From: Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma

Polymorphism

Genotype

CT (+) Tumors, n (%)

CT (-) Tumors, n (%)

χ2

P*

MTHFR 677 C>T (rs1801133)

CC

13 (62%)

7 (24%)

7.30

0.03

CT

5 (24%)

15 (52%)

TT

3 (14%)

7 (24%)

MTHFR 1298 A>C (rs1801131)

AA

13 (62%)

14 (48%)

0.91

0.63

AC

7 (33%)

13 (45%)

CC

1 (5%)

2 (7%)

MTR 2756 A>G (rs1805087)

AA

14 (67%)

22 (76%)

0.51

0.53**

AG

7 (33%)

7 (24%)

GG

0 (0%)

0 (0%)

MTRR 66 A>G (rs1801394)

AA

4 (19%)

9 (31%)

0.92

0.63

AG

10 (48%)

12 (41%)

GG

7 (33%)

8 (28%)

RFC 80 G>A (rs1051266)

GG

6 (29%)

12 (41%)

1.90

0.39

GA

9 (43%)

13 (45%)

 

AA

6 (29%)

4 (14%)

  
  1. * Chi-square (2 degrees of freedom); ** Fisher’s exact test, two sided.