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Table 2 Distribution of individual genotypes among CT (+) and CT (-) tumors

From: Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma

Polymorphism Genotype CT (+) Tumors, n (%) CT (-) Tumors, n (%) χ2 P*
MTHFR 677 C>T (rs1801133) CC 13 (62%) 7 (24%) 7.30 0.03
CT 5 (24%) 15 (52%)
TT 3 (14%) 7 (24%)
MTHFR 1298 A>C (rs1801131) AA 13 (62%) 14 (48%) 0.91 0.63
AC 7 (33%) 13 (45%)
CC 1 (5%) 2 (7%)
MTR 2756 A>G (rs1805087) AA 14 (67%) 22 (76%) 0.51 0.53**
AG 7 (33%) 7 (24%)
GG 0 (0%) 0 (0%)
MTRR 66 A>G (rs1801394) AA 4 (19%) 9 (31%) 0.92 0.63
AG 10 (48%) 12 (41%)
GG 7 (33%) 8 (28%)
RFC 80 G>A (rs1051266) GG 6 (29%) 12 (41%) 1.90 0.39
GA 9 (43%) 13 (45%)
  AA 6 (29%) 4 (14%)   
  1. * Chi-square (2 degrees of freedom); ** Fisher’s exact test, two sided.