Haplotypea | Genotype | N | Controls | Type 2 diabetes | OR (95% CI) | P | aOR (95% CI)b | P |
---|---|---|---|---|---|---|---|---|
111 | n | 1048 | 374 | 674 | ||||
- - | 608 | 219 (58.6) | 389 (57.7) | Reference | ||||
111 - | 376 | 140 (37.4) | 236 (35.0) | |||||
111 111 | 64 | 15 (4.0) | 49 (7.3) | 1.12 (0.91–1.38) | 0.30 | 1.00 (0.75–1.34) | 0.98 | |
Frequency | 0.23 | 0.25 | ||||||
112 | n | 1048 | 374 | 674 | ||||
- - | 224 | 82 (21.9) | 142 (21.1) | Reference | ||||
112 - | 544 | 183 (48.9) | 361 (53.6) | |||||
112 112 | 280 | 109 (29.1) | 171 (25.4) | 0.94 (0.78–1.13) | 0.51 | 0.95 (0.74–1.22) | 0.67 | |
Frequency | 0.54 | 0.52 | ||||||
121 | n | 1048 | 374 | 674 | ||||
- - | 823 | 296 (79.1) | 527 (78.2) | Reference | ||||
121 - | 205 | 72 (19.3) | 133 (19.7) | |||||
121 121 | 20 | 6 (1.6) | 14 (2.1) | 1.07 (0.81–1.40) | 0.64 | 1.40 (0.99–1.99) | 0.06 | |
Frequency | 0.11 | 0.12 | ||||||
122 | n | 1048 | 374 | 674 | ||||
- - | 1039 | 372 (99.5) | 667 (99.0) | Reference | ||||
122 - | 9 | 2 (0.5) | 7 (1.0) | |||||
122 122 | 0 | 0 (0.0) | 0 (0.0) | 1.95 (0.40–9.44) | 0.41 | 3.87 (0.61–24.52) | 0.15 | |
Frequency | 0.01 | 0.01 | ||||||
221 | n | 1048 | 374 | 674 | ||||
- - | 853 | 298 (79.7) | 555 (82.3) | Reference | ||||
221 - | 186 | 72 (19.3) | 114 (16.9) | |||||
221 221 | 9 | 4 (1.1) | 5 (0.7) | 0.84 (0.63–1.14) | 0.27 | 0.73 (0.48–1.10) | 0.13 | |
Frequency | 0.11 | 0.09 | ||||||
211 | n | 1048 | 374 | 674 | ||||
- - | 1041 | 369 (98.7) | 672 (99.7) | Reference | ||||
211 - | 7 | 5 (1.3) | 2 (0.3) | |||||
211 211 | 0 | 0 (0.0) | 0 (0.0) | 0.22 (0.04–1.14) | 0.07 | 0.32 (0.03–2.92) | 0.31 | |
Frequency | 0.01 | 0.001 | ||||||
212 | n | 1048 | 374 | 674 | ||||
- - | 1043 | 372 (99.5) | 671 (99.6) | Reference | ||||
212 - | 5 | 2 (0.5) | 3 (0.4) | |||||
212 212 | 0 | 0 (0.0) | 0 (0.0) | 0.83 (0.14–5.00) | 0.84 | - | / | |
Frequency | 0.003 | 0.002 | ||||||
222 | N | 1048 | 374 | 674 | ||||
- - | 1030 | 370 (98.9) | 660 (97.9) | Reference | ||||
222 - | 18 | 4 (1.2) | 14 (2.1) | |||||
222 222 | 0 | 0 (0.0) | 0 (0.0) | 1.96 (0.64–6.00) | 0.24 | 1.20 (0.28–5.04) | 0.81 | |
Frequency | 0.01 | 0.01 |