From: Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes
COPD | Control | pvalue for | |
---|---|---|---|
n = 51 | n = 51 | Mann–Whitney test | |
Gender (male) | 30 | 28 | >0.05 |
Ethnicity (white) | 45 | 50 | >0.05 |
Age (years)a | 65.33 ± 8.91 | 63.61 ± 9.40 | >0.05 |
BMI (kg/m2)a | 25.75 ± 5.71 | 26.82 ± 3.89 | >0.05 |
FEV1 (% predicted) | 42.90±19.03 | 86.14±11.72 | 0.000 |
FEV1/FVC (% predicted) | 67.92±19.58 | 105.24±70.28 | 0.000 |
Smoking Status | |||
Never/ Former/ Current | 5/ 34/ 12 | 22/ 25/ 4 | χ2 0.000 |
Cigarettes-yearb | |||
Current smoking | 8059 (3650–14600) | 7026 (3650–10950) | >0.05 |
Former smoking | 10490 (1095–25550) | 5621 (1095–14600) | 0.003 |
Smoking Duration | |||
>30 years | 36 | 9 | χ2 0.000 |
COPD Statusc | |||
Mild | 8 | - | - |
Moderate | 16 | - | - |
Severe | 16 | - | - |
Very Severe | 11 | - | - |