Skip to main content
Figure 1 | BMC Medical Genetics

Figure 1

From: Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes

Figure 1

Correlations between polymorphisms in DNA repair genes, comet assay and BMCyt assay in COPD patients. A) Damage Index in alkaline Comet assay in blood of COPD patients with variant genotypes in XRCC3 (ThrMet+MetMet). The alkaline basal damage index in COPD patients correlated positively with VEF1 (r 0.336; p=0.045); B) % Condensed chromatin cells (CC) in COPD patients with variant genotypes in XRCC1 (ArgGln+GlnGln) correlated negatively with VEF1 (r -0.404; p= 0.029); C) % Karyorrhectic cells (KR) in COPD patients XRCC1 (ArgGln+GlnGln) correlated negatively with VEF1 (r -0.398; p= 0.044). COPD patients - black points. Statistical analysis was performed by Spearman’s rho Test.

Back to article page