Skip to main content

Table 4 Association of the APOAI rs670G > A genotype with total cholesterol and LDL-C

From: Re-sequencing of the APOAI promoter region and the genetic association of the -75G > A polymorphism with increased cholesterol and low density lipoprotein levels among a sample of the Kuwaiti population

Variable

OR 95% CI

P-value

 

A. Cholesterol grouped (High vs Normal)

 

APOA rs670

1.77 (1.17–2.69)

0.006

Age

1.02 (1.00–1.03)

0.002

Sex

1.12 (0.74–1.70)

0.579

BMI

1.05 (1.02–1.09)

0.0004

 

B. LDL grouped (Normal vs Abnormal)

 

APOA rs670

1.66 (1.10–2.51)

0.014

Age

1.02 (1.00–1.03)

0.003

Sex

1.77 (1.18–2.65)

0.005

BMI

1.05 (1.02–1.08)

0.0006

  1. The values represented include the odds ratio, confidence interval and p values as evaluated by multivariate analysis using logistic regression in 549 Kuwaiti individuals grouped based on their TC and LDL-C values according to the population normal reference values. Multivariate analysis shows the APOAI rs670 to be a significant (p < 0.05) independent predictive factor when controlling for age, sex and BMI for both cholesterol and LDL levels.