Table 3 MS-MLPA analytical sensitivity testing: analysis of the samples dilution series ranging from 100% to 2.5% of DNA from a full-mutated patient
From: MS-MLPA analysis for FMR1 gene: evaluation in a routine diagnostic setting
Mixtures of dilution series | FMR1D*:U** range | CI 95% (l. inf. – l. sup.) |
|---|---|---|
75% | 0.47 – 0.88 | 0.432- 0.745 |
50% | 0.32 – 0.65 | 0.316- 0.521 |
25% | 0.17 – 0.3 | 0.178- 0.270 |
10% | 0.06 – 0.14 | 0.323- 0.780 |
5% | 0.04 – 0.09 | 0.111- 0.506 |
2.5% | 0.00-0.08 | 0.001-0.062 |