Table 1 Characteristics of human pancreatic donors
From: DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets
Phenotypes | Non-diabetic donors | Type 2 diabetes donors | p-value |
|---|---|---|---|
n (male/female) | 55 (29/26) | 10 (6/4) | |
Age (years) | 56.7 ± 9.8 | 57.8 ± 12.6 | 0.74 |
BMI (kg/m2) | 25.9 ± 3.6 | 28.1 ± 4.6 | 0.17 |
HbA1c | 5.7 ± 0.8 | 7.1 ± 1.2 | 0.00017 |
Basal insulin secretion (ng/islet/h) | 0.37 ± 0.27 | 0.22 ± 0.17 | 0.22 |
Glucose-stimulated insulin secretion (ng/islet/h) | 1.42 ± 0.95 | 1.05 ± 1.56 | 0.045 |
Stimulation index | 8.57 ± 9.62 | 3.07 ± 1.36 | 0.027 |