Figure 3
From: Genetics of coronary artery calcification among African Americans, a meta-analysis
LocusZoom plots of the 9p21 region. Fine mapping of the 9p21 region using LOCUS ZOOM [39]. The top plot uses data from MIGen [3] for the Caucasian CHD associations (lead EA SNP is rs4977574 on right and lead AA SNP from CARe CHD is rs6475606 on left). The second plot demonstrates the AA CHD associations, highlighting the same two SNPs as the first graph [11]. The third plot depicts the EA CAC associations [22] and its lead SNP, rs1333049. The final plot depicts our AA CAC associations with lead SNP rs16905644 (AA CAC meta-analysis associations for all these SNPs are in Additional file 1: Supplemental Table S5). In all plots, the region associated with EA is broader than the region associated with AAs and the top results for AA CAC are in the same region as that associated with CHD in AA [11].