Table 2 Mutations found in the BRCA2 gene in consecutive breast or ovarian cancer patients
Nucleotide change | Effect on protein | Case (n=1075) | Diagnosis/age |
|---|---|---|---|
c.646delG | A216 (229stop) | 3 | BC/39,44,58 |
c.658delGT | V220 (223stop) | 4 | BC/43,51,55,73 |
c.5244delC | S1748 (1748stop) | 0 | |
c.7316delG | G2439 (2468stop) | 0 |