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Table 2 Mutations found in the BRCA2 gene in consecutive breast or ovarian cancer patients

From: BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sporadic cancer patient surveilling for hidden high-risk families

Nucleotide change Effect on protein Case (n=1075) Diagnosis/age
c.646delG A216 (229stop) 3 BC/39,44,58
c.658delGT V220 (223stop) 4 BC/43,51,55,73
c.5244delC S1748 (1748stop) 0  
c.7316delG G2439 (2468stop) 0