Table 1 The Carrier rate and mutation spectrum of deafness-associated genes in 7,263 hearing subjects
Gene | Nucleotide change | Carrier number | Carrier rate (%) |
|---|---|---|---|
GJB2 gene | c. 35 del G | 1 | 0.01% |
c. 176_191 del 16 bp | 7 | 0.10% | |
c. 235 del C | 128 | 1.76% | |
c. 299_300 del AT | 28 | 0.38% | |
GJB3 gene | c. 538 C > T | 9 | 0.12% |
SLC26A4 gene | c. 2168 A > G | 19 | 0.26% |
c. 919–2 A > G | 90 | 1.24% | |
mtDNA 12S rRNA gene | m. 1494 C > T | 3 | 0.04% |
m. 1555 A > G | 18 | 0.25% |