|
SNP
|
1/2
|
Subgroup (n)
|
11
|
12
|
22
|
MAF (%)
|
Allelic P-value
|
OR (95% CI)
|
|---|
|
IL2/IL21
| | | | | | | | |
|
rs2069762
|
C/A
|
Controls (n=760)
|
61 (8.03)
|
315 (41.45)
|
384 (50.53)
|
437 (28.75)
| | |
| | |
Uveitis (n=195)
|
17 (8.71)
|
85 (43.60)
|
93 (47.69)
|
119 (30.51)
|
0.49
|
1.09 (0.85-1.40)
|
|
rs6822844
|
T/G
|
Controls (n=760)
|
15 (1.97)
|
156 (20.53)
|
589 (77.50)
|
186 (12.24)
| | |
| | |
Uveitis (n=196)
|
2 (1.02)
|
28 (14.29)
|
166 (84.69)
|
32 (8.16)
|
0.02*
|
0.64 (0.43-0.94)
|
|
rs907715
|
T/C
|
Controls (n=760)
|
81 (10.66)
|
330(43.42)
|
349(46.92)
|
492 (32.37)
| | |
| | |
Uveitis (n=196)
|
26 (13.27)
|
70 (35.71)
|
100 (51.02)
|
122 (31.12)
|
0.64
|
0.94 (0.74-1.20)
|
|
IL2RA
| | | | | | | | |
|
rs12722495
|
G/A
|
Controls (n=760)
|
3 (0.39)
|
114 (15.00)
|
643 (84.61)
|
120 (7.90)
| | |
| | |
Uveitis (n=196)
|
2 (1.02)
|
29 (14.80)
|
165 (84.18)
|
33 (8.42)
|
0.73
|
1.07 (0.72-1.60)
|
|
rs2104286
|
C/T
|
Controls (n=760)
|
19 (2.50)
|
270 (35.53)
|
471 (61.97)
|
308 (20.26)
| | |
| | |
Uveitis (n=196)
|
10 (5.10)
|
60(30.61)
|
126 (64.29)
|
80 (20.41)
|
0.95
|
1.01 (0.77-1.33)
|
|
rs11594656
|
T/A
|
Controls (n=760)
|
84 (11.05)
|
346(45.53)
|
330(43.42)
|
514 (33.82)
| | |
| | |
Uveitis (n=196)
|
23 (11.79)
|
69 (35.38)
|
103 (52.82)
|
115 (29.49)
|
0.10
|
0.82 (0.64-1.04)
|
|
IL2RB
| | | | | | | | |
|
rs743777
|
G/A
|
Controls (n=760)
|
86(11.32)
|
349(45.92)
|
325(42.76)
|
521 (34.28)
| | |
| | |
Uveitis (n=195)
|
26 (13.40)
|
72 (37.11)
|
96 (49.48)
|
124 (31.96)
|
0.39
|
0.90 (0.71-1.14)
|
-
*P
FDR-corrected=0.17.
- SNP; Single Nucleotide Polymorphism.
- MAF; Minor Allele Frequency.
- OR; Odds Ratio.
