From: Contribution of the PALB2 c.2323C>T [p.Q775X] Founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent
Syndrome
Number of families1
Unilateral BC
Bilateral BC
BC and OC
OC
Mean age in years of BC (age range)
Mean age in years of OC (age range)
HBC
48 [10]
45
3
0
46 (30–65)
n/a
HBOC
23 [4]
14
2
1
6
44 (25–55)
51 (31–74)
Total
71 [14]
59
5
46 (25–65)
