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Table 1 Clinical characteristics of patients with bronchial mucosa tissues for DNA Methylation chip

From: Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy

Clinical profile

NC

Atopic asthmatics

Non atopic asthmatics

P-value

NC vs BA

in BA

Number

7

10

7

  

Age, years (range)

50 (22–71)

35 (21–60)

47 (28–78)

0.288

0.133

Sex, male, n(%)

1 (14.3)

4 (40)

1 (14.3)

0.629

0.338

exsmoker/nonsmoker (%)

0 / 7

2 / 8

1 / 6

0.299

0.677

Positive skin test rate (%)*

ND

100*

0

-

0.00005

FVC (% predicted)

89.20 ± 10.18

79.50 ± 16.89

90.80 ± 22.26

0.349

0.371

FEV1 (% predicted)

102.00 ± 16.84

78.50 ± 22.54

90.60 ± 20.77

0.119

0.44

FEV1/FVC (% predicted)

85.80 ± 6.18

77.00 ± 15.12

76.20 ± 6.10

0.168

0.513

Body mass index (kg/m2)

23.37 ± 4.08

25.31 ± 1.66

25.92 ± 3.20

0.497

0.37

Total IgE (IU/M)

37.2

663.95 ± 784.99

111.28 ± 99.90

0.267

0.036

Dp. specific IgE (score)

ND

4 (2–6)

0

-

0.0005

Df. specific IgE (score)

ND

4 (2–6)

0

-

0.0005

  1. Data are presented as mean ± standard deviation or as median (range).
  2. *Positive skin prick test to house dust mites(D. pteronyssinus, or D. farina).
  3. BA:Bronchial asthma; NC:Normal control.