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Table 3 Proportion of anti-glycans antibody positive subjects among the CD probands and the HFDRs

From: The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn’s disease

  ASCA positive ALCA positive ASCA or ALCA positive
  n % 95% CI p value n % 95% CI p value n % 95% CI p value
CD probands (n=39) 21 53.8 [38.6-68.4] p<0.0001 15 38.4 [24.9-54.1] p=0.0008 23 58.9 [43.4-72.9] p<0.0001
HFDR (n=39) 4 10.3 [4.1-23.6]   3 7.7 [2.7-20.3]   6 15.4 [7.3-29.7]  
  1. ASCA positivity was according to the 50 AU threshold and ALCA positivity according to the 60 AU threshold.