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Table 1 Allelic frequencies of the p.C10X mutation in the populations under study

From: The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn’s disease

  

p.C10X MAF

95% CI

Comparison between the 4 groups (dof=3)

Comparison (dof=1)

Comparison (dof=1)

1

CD patients

0.243

[0.183-0.316]

p = 0.09

1 vs. 2

1+2 vs. 3+4

2

Healthy subjects from CD families

0.238

[0.177-0.309]

   
     

p=0.89

 
      

p = 0.06

3

French control families

0.347

[0.251-0.471]

 

3 vs. 4

 
     

p = 0.53

 

4

HapMap CEU

0.315

[0.271-0.361]

   
  1. Frequencies are those determined in pedigrees using the Haploview software. All frequencies comparisons were performed with the CLUMP software and robust p values were obtained following 100,000 Monte Carlo permutations. (MAF: minor allele frequency, dof: degree of freedom).
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BMC Medical Genetics

ISSN: 1471-2350

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